Morten Bro Nielsen
 
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Ph.D. - Medical Image Registration and Surgery Simulation

Description
Advisers: Prof. Knut Conradsen, Institute of Mathematical Modelling, Technical University of Denmark
Dr. Bjarne K. Ersbøll, Institute of Mathematical Modelling, Technical University of Denmark
Censors:

Dr. Nicholas Ayache, INRIA Epidaure, France
Prof. Mike Brady, Oxford University, UK
Dr. Allan Aasbjerg, Institute of Mathematical Modelling, Technical University of Denmark

Medical images are fundamentally models of the human body sampled at one point in time. As such they have tremendous value in medicine since they provide a snapshot in which diseases and mal-formations usually can be diagnosed and treatments can be planned. But in some cases the behavior of the tissue over time or the reaction of the tissue to external stimuli can also be very important. An example is the development over time of some tumors that can be used to predict the development of the tumor. Another example is planning of cranio-facial surgery on children. In children it is important to know what the future growth of the child will be. One way to predict this is by knowing something about the history of the child's development. 

If only one snapshot of the patient is available, the only alternative is to try to model the physical behavior of the tissue in the patient. If a snapshot of the tissue and a physical model of it is available, theory says that it should be possible to predict the behavior of the tissue within reasonable limits.

This dissertation is about such models of human tissue and the use of these models in different medical applications to model growth, deformation, and other changes in a patient - based on one or a few 3D images of the patient. 

Continuum models of elasticity and viscous fluids form the basis for these models. They are studied in detail, and this knowledge is used as a basis for the applications described below.

To read about the projects that I worked on as part of my Ph.D., click here.

 

 

© Copyright 2003 by Morten Bro Nielsen. All rights reserved.